National Magnetic Resonance Facility at Madison

NMRFAM operations during the COVID-19 pandemic – Essential operations only

UW-Madison is currently operating under essential operations ONLY. This means that NMRFAM is not operating under normal procedures.

• Standard NMR calendars are suspended while research operations are restricted. You will not be charged for time that you have reserved but cannot use because of COVID-19. If you currently have time reserved, please contact Lai Bergeman (lai.bergeman@wisc.edu) and Milo Westler (milo@nmrfam.wisc.edu) to confirm cancellation of your time or to discuss the possibility of running your experiment if it meets the guidelines below.
• Limited research operations are ongoing. Samples can be changed only when staff are already in the facility to perform essential operations. No experiments requiring frequent sample changes or hands-on staff time in the facility will be performed. Long-running experiments may be run through remote operations in consultation with NMRFAM staff. If you have a sample already at NMRFAM and wish to collect additional data, this is your chance! Please contact Lai Bergeman (lai.bergeman@wisc.edu) and Milo Westler (milo@nmrfam.wisc.edu) if you would like to discuss experiments that meet these requirements.
• There will be no entrance to any part of the facility except for essential staff. No staff will be present except during essential procedures (cryogen fills, maintenance, etc.). Staff will be available through email and are happy to discuss project planning, data analysis, etc.
• Shipping and receiving is currently operating at a very reduced capacity. Please do NOT ship your precious, isotopically-labeled samples to us because we cannot guarantee prompt receipt and proper handling.
• There will be no drop-off sample service on Tuesdays and Thursdays.
• The June NMRFAM workshop will most likely not be held on-site. Stay tuned for further information regarding a possible virtual workshop.

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The National Magnetic Resonance Facility at Madison (NMRFAM) is a resource for biomolecular nuclear magnetic resonance (NMR) spectroscopy and related techniques that aims to expand the frontiers of biomolecular NMR spectroscopy through technology, research, and development programs.

| Become an NMRFAM Collaborator | Become an NMRFAM User |

Learn more about how we can help advance your research in the following areas:

Research Center Focus

What is NMRFAM

The National Magnetic Resonance Facility at Madison (NMRFAM) is a Biomedical Technology Research Resource (BTRR), a National Institutes of Health (NIH) / National Institute of General Medical Sciences (NIGMS)-funded, shared instrumentation laboratory located at the University of Wisconsin-MadisonDepartment of Biochemistry.

In addition to assisting users in their research, NMRFAM actively seeks collaborative projects that present substantial technical challenges and serve to drive the development of the Center’s Technology Research and Development (TR&D) Projects.

NMRFAM’s Current TR&D Projects

• Automation in NMR data collection, spectral analysis and assignment, and structure determination of small- and moderate-sized proteins and RNA molecules.
• Determination of the structure, dynamics, and functional properties of challenging proteins and nucleic acids and their complexes by NMR and SAXS approaches.
• NMR-based studies of metabolomics and natural products including LC-MS solid-phase extraction of molecules of interest.

NMRFAM’s Grants and Funding Sources