NMRFAM News!
As part of the Network for Advanced NMR (NAN), there are two new 1.1 GHz NMR spectrometers available for use by the broader NMR community. The NMRFAM 1.1 GHz NMR is primarily a solid-state instrument, while the CCRC 1.1 GHz NMR Is configured for solution.
The new 1.1 GHz SSNMR spectrometer at NMRFAM is named Lakenvelder.
Available probes for Lakenvelder include:
BlackFox 1.6 mm HCN/HPC E-Free with lock, for biological samples
Phoenix 1.2 mm and 1.6 mm HFXY with lock, for general fast-MAS purposes
Phoenix 3.2 mm HX for low-gamma nuclei
Bruker HCN 0.7 mm for ultrafast MAS
Details available on the NAN resource connector or our Instruments page
Submit project requests at https://usnan.nmrhub.org/access-uhf
A short description of your project, planned experiments, justification for ultra-high field time, and preliminary spectrum at lower field to demonstrate sample quality is required.
Project proposals are reviewed on the basis of need for GHz NMR time to ensure maximal impact of these instruments. Users who are granted time are added to the reviewer pool to ensure fair access for the community.
Once a project is approved, experiments are scheduled by the individual facilities based on the technical requirements of the planned experiments. The goal is to maximize data collection and minimize spectrometer reconfiguration, and to coordinate projects requiring implementation of new experiments with staff availability.
Rates are $20/hr for 1.1 GHz NMR time. Please contact us directly if cost is an issue.
All data is automatically transferred to the NAN data archive upon completion of data acquisition, providing multiple ways to access your data directly from NMRFAM or through the NAN data browser. This also facilitates publication of your 1.1 GHz raw data sets with unique identifiers, and sample data, processed data, and reference IDs for other repositories (BMRB, PDB, etc.) may be directly linked to the data set before publication.
About NMRFAM
National Magnetic Resonance Facility at Madison (NMRFAM) is a resource that aims to expand the frontiers of biomolecular NMR spectroscopy in solution and the solid state, to ease access for scientists to state-of-the-art spectroscopic methods, and to disseminate technologies broadly to the user community. Our overall goal is to continue a tradition of providing excellent NMR service to the biomedical research community.
NMRFAM provides access to high field (600-900 MHz) solution and solid-state NMR instrumentation and expert staff to assist researchers who would like assistance in experimental design, data acquisition or data analysis. Please contact us with your project ideas and instrumentation needs.
User Program (R24)
NMRFAM is an unique resource for high field NMR that has been supported by NIH (NCRR and/or NIGMS) through the P41 program for over 30 years. Our overall goal for this proposal is to continue this tradition of providing excellent NMR service to the biomedical research community
Technology Development (P41)
There are four areas of focus for technology development at NMRFAM, improving performance of the NMR spectrometer, experimental design, properties of the sample (quality and significance), and ability to interpret the data.
Network for Advanced NMR (NSF)
NMRFAM is a part of the Network for Advanced NMR (NAN) which aims to allow for easier access to both novice and expert users to instruments, data, and knowledge of NMR.
NMRFAM Staff
Click here for a current listing of NMRFAM staff and contact information
NMRFAM Sponsor Acknowledgements
All publications resulting from research at NMRFAM must acknowledge the facility and its funding sources (this is a requirement of the grants that support NMRFAM).
This study made use of the National Magnetic Resonance Facility at Madison, an NIH Biomedical Technology Research Resource Center NIH R24GM141526. Helium recovery equipment, computers, and infrastructure for data archive were funded by the University of Wisconsin-Madison, NIH R24GM141526.
For use of the following specific spectrometers, please cite the corresponding instrumentation grant:
Lakenvelder NSF 1946970 (National Science Foundation Mid-Scale Research Infrastructure Big Idea)
Girolando S10OD034243
Ayrshire, Phoenix HFXY 1.6 mm Probe R35GM118131 and R01GM095839
Kerry S10RR023438
Kurgan S10RR025062