• NMRFAM-Spectrometers

NMRFAM “Devon” Avance III-500II

Bruker 500IIDevon is a Bruker Instruments Avance III 500 MHz NMR spectrometer with a 11.75 T standard bore magnet. This instrument is equipped with a cryogenic probe/Broadband/HRMAS/CPMAS.

Console Capabilities

The console of devon is equipped with 3 RF channels, 4 amplifiers, and the capability generate 3-axis gradients of arbitrary shape. Each RF channel is capable of generating hard and shaped pulses over any nucleus. The four amplifiers consist of two linear amps covering the x-nucleus frequencies up to phosphorus, one for hydrogen and one for deuterium.

The controlling computer is an HP desktop computer running CentOS Linux. The Bruker software, TopSpin, should be capable of executing any desired multi-dimensional experiment, with the only limits being the type of nuclei observed.

Available Probes

  • 1H(13C,15N) 5 mm cryogenic probe – cold swappable
  • 1H(X) 5 mm probe
  • HRMAS – 1H(13C,15N) 4 mm rotor
  • CPMAS- Low-e 1H(13C,15N) 3 mm rotor
  • CPMAS- 1H(X) 4 mm rotor


The base rate for time on this machine is $6.00/hour for publishable work or $200/hour for proprietary work.

Become an NMRFAM User
Contacts | Map | Policy
Instrumentation w/Rates
Pulse Programs
Remote Access to NMRFAM
Spectrometer Live Calendar
Sundial (Request NMR Time)
Software Tools
e-News Sign-Up

Biochemistry 800 - Practical Nuclear Magnetic Resonance Theory 

Biochemistry 801 - Biochemical Applications of Nuclear Magnetic Resonance 

"The Future of NMR-Based Metabolomics, Current Opinion in Biotechnology (2017), pp. 34-40

Documents on the use of the Bruker-Axs Nanostar,SAXS instrument and analysis of SAXS data are now available.

NMRFAM-SPARKY Distribution - the popular NMR analysis program SPARKY recompiled (including updated python and Tcl/Tk) with incorporation of PINE-Sparky, enhancements to import/export to the structural analysis program CYANA, and other useful python extensions.

ADAPT-NMR Enhancer: Complete Package for Reduced Dimensionality in Protein NMR Spectroscopy

RNA-PAIRS: RNA Probabilistic Assignment of Imino Resonance Shifts

PACSY, a Relational Database Management System for Protein Structure and Chemical Shift Analysis 


Donate to NMRFAM. US tax-deductible donation can be made to NMRFAM
Please write check payable to "UW Foundation, Account 112152802"  
And mail to: 
Attn: Sarah Lynn Traver Saunders
Associate Administrative Program Specialist 
University of Wisconsin-Madison 
433 Babcock Drive 
Madison, WI 53706 
Tel: 608-265-2507 or email 


1st: Lai Bergeman 
Rm 171; Phone 262-3173

2nd: Milo Westler
Rm B160; Phone 263-9599

3rd: Paulo F. Cobra
Rm B224; Phone 265-3303

4th: Marco Tonelli
Rm B160; Phone 263-9493

5th: John Markley
Rm 171A; Phone 263-9349

We welcome your questions and feedback!

NMRFAM Established 1987